Masane is the latest in a long line of female bearers of the Witchblade, an arcane and ancient weapon of unthinkable power. Conscripted into the service of the Doji Group, she is charged with destroying X-Cons, a murderous scourge of mysterious origin stalking the streets of Tokyo.

The doting mother of Rihoko, and more than a little flighty, Masane is willing to make any sacrifice to provide for the young girl that provides her only peace.